Extracorporeal Blood Oxygenation and Ozonation (EBOO) is a way for patients to support overall wellness through blood filtration and ozone therapy. This treatment can help those dealing with fatigue, inflammation, or immune system concerns. At Orchidia Medical Group, we provide EBOO treatments in Naples, FL, as one of our functional and regenerative therapies.
What Is EBOO Ozone Therapy?
EBOO stands for Extracorporeal Blood Oxygenation and Ozonation, a method that combines oxygen therapy with ozone to support systemic health. It is used for patients dealing with persistent inflammation, chronic infections, or toxin buildup. EBOO circulates blood through a closed system outside the body, allowing a larger volume to be filtered and oxygenated throughout each session.
What Is Ozone?
Ozone is a molecule made up of three oxygen atoms (O₃), unlike the oxygen we breathe, which has two (O₂). The ozone used in EBOO is medical-grade and produced by passing pure oxygen through an ozone generator, creating a precise mixture of oxygen (O₂) and ozone (O₃). We do not use environmental ozone or ozone from air-based sources, and the ozone never enters the lungs. In this treatment, the ozone interacts with the blood inside a closed, sterile system and never enters the body as a gas.
How EBOO Therapy Works
During EBOO, blood is drawn from a vein through the closed loop system, where it passes through a dialysis filter, and then returns the blood to the body through a second vein. As the blood moves through the system, it is exposed to controlled ozone and oxygen. This step-by-step filtration process helps clear byproducts like damaged cells, microbes, and heavy metals. Because the blood is never exposed to open air, the risk of contamination remains low. Sessions typically take less than an hour and are spaced out over several weeks.
Health Benefits of EBOO
Treatment for Chronic Fatigue and Fibromyalgia
Patients with conditions like fibromyalgia and chronic fatigue deal with persistent pain, low energy, and difficulty recovering from everyday activity. This natural detox therapy for chronic fatigue may offer relief by supporting oxygen delivery and helping clear out toxins and inflammatory byproducts that contribute to fatigue.
Inflammation Reduction
Chronic inflammation often contributes to autoimmune disease, joint pain, and tissue damage. EBOO therapy reduces inflammatory markers in the bloodstream by improving oxygenation and filtration. If you are looking for the best IV therapy for inflammation, you may find this approach helpful when symptoms persist despite other interventions.
Improved Circulation and Cardiovascular Health
In some cases, poor circulation leads to pain, cold extremities, or delayed healing. Because EBOO supports oxygen delivery and helps clear the blood of waste and oxidants, it may help in improving blood flow. If you want to know how to improve circulation naturally, we can discuss this option.
Immune Modulation and Infection Support
The interaction between ozone and blood can stimulate immune cells and influence the body’s inflammatory response. EBOO is sometimes used as a complementary tool for managing chronic infections or recurrent illness. It promotes internal balance while filtering harmful byproducts and may help regulate immune overactivity without suppressing its function.
Detoxification and Anti-Aging
Some patients turn to EBOO to help support detox pathways and reduce the buildup of environmental toxins, heavy metals, or metabolic waste. Blood ozonation and filtration may promote more efficient cellular repair and improved energy. EBOO ozone treatments can provide benefits for skin health, energy levels, and aging-related fatigue.
Who May Benefit From EBOO?
You may benefit from EBOO ozone therapy if you are dealing with chronic fatigue, autoimmune disorders like rheumatoid arthritis or multiple sclerosis, or persistent inflammation that does not respond well to standard approaches. We often see interest from patients with long COVID, mold exposure, metal toxicity, or chronic infections that continue to affect quality of life.
If you are managing cardiovascular conditions, circulation issues, or joint pain, this therapy may help support those systems by improving oxygenation and reducing internal stress. Patients with skin conditions, eye diseases, or concerns related to aging and cellular repair can also explore EBOO as part of their wellness plan. It can complement conventional treatments, and it can also be used on its own.
EBOO Treatments Step by Step
Placement of IV Lines
We start by placing two intravenous lines, including one to draw the blood and one to return it after treatment. The IV placement is similar to what you might experience during a routine blood draw, and we use techniques to minimize discomfort. Most patients sit or recline comfortably during this part of the process. Once the IVs are in place, we begin the closed-loop treatment.
Filtration and Dialysis
After we draw the blood, it moves through a dialysis-style filter that removes harmful substances. This includes waste from damaged cells, heavy metals, metabolic debris, and byproducts from chronic infections or inflammation. The filtration process helps reduce the overall toxic burden on your body and allows your organs to function with less strain. Because the system continuously circulates your blood, it provides a more thorough cleansing than ozone methods that treat only a small sample.
Ozonation and Oxygenation
Once the blood is filtered, we expose it to a calibrated mix of ozone and oxygen. The ozone interacts with components in the blood to create signaling molecules that can influence how your body manages inflammation, immunity, and oxidative stress. At the same time, the oxygenation step supports tissue repair, energy production, and circulation by enhancing the way your red blood cells deliver oxygen. We use medically guided parameters to customize the treatment for you.
Reinfusion
Once the blood has been filtered and oxygenated, we return it to your body through the second IV line. The system stays fully closed the entire time, so we control the process carefully and keep everything sterile. Reinfusion completes the cycle and allows your body to start responding to the effects of ozone and filtration. The whole session takes about 45 minutes, and you stay seated and relaxed throughout. You may feel lighter, clearer, or more balanced after your treatment.
EBOO Myths and Misconceptions
Does EBOO Kill Good Cells?
Ozone does not destroy healthy cells in this setting. Red and white blood cells are resistant to the mild oxidative stress of EBOO. Instead, ozone interacts with weaker cells, damaged membranes, and pathogens, triggering the body’s own antioxidant and repair systems.
How Is This Different from Chelation or Dialysis?
EBOO is not the same as chelation or traditional dialysis. Chelation uses compounds to bind metals, while dialysis filters waste for people with kidney failure. EBOO uses a dialysis-style filter to support detox and immune balance in otherwise healthy individuals, but the addition of ozone and oxygen makes the process entirely different.
Is EBOO the Same as 10-Pass Ozone?
Although both use ozone, they work differently. 10-pass ozone treats small amounts of blood in batches and reintroduces it after each pass. EBOO uses continuous circulation, allowing larger volumes of blood to be filtered, oxygenated, and ozonated all at once. The treatment is gentler and more consistent for some patients, especially those who do not tolerate high-pressure methods.
EBOO Treatment Protocol
- Initial Evaluation: We start by going over your health history, current symptoms, and what you want to get out of treatment. Through our consultation, we will decide if EBOO is the right fit and customize the ozone concentration and session plan.
- Frequency: Most patients begin with three sessions, spaced about a week apart. We may suggest repeating the series twice a year or adjusting the schedule to fit your goals.
- Session Duration: Each EBOO treatment takes about 45 to 60 minutes. You stay awake during the process and can usually go back to your normal routine once the session is done.
- Treatment Comfort: You’ll be seated or reclined comfortably while we monitor the system and manage the IVs. We stay close by in case you need anything, and most patients find the experience easy to tolerate.
Preparation and Aftercare Guidance
Pre-Treatment Advice
- Eat a Light Meal: Have something small to eat about one to two hours before your appointment. You do not need to fast, and showing up on an empty stomach may leave you feeling lightheaded during the session.
- Hydrate Well: Drink plenty of water before your visit, and consider an electrolyte drink the night before or the morning of your treatment. Staying hydrated helps with blood flow and makes IV placement easier.
- Dress for Comfort: Wear loose-fitting clothing with sleeves that can roll up easily. We will need to access your arms for IV placement without making you feel restricted during the session.
- Avoid Alcohol: Skip alcohol the day before and the day of your appointment. Even small amounts can make your liver work harder and may interfere with how your body responds to ozone.
- Take Prescribed Medications as Usual: If you take daily medications, you will likely still be able to take them unless you are taking blood thinners. Let us know what you use so we can review it.
Post-Treatment Advice
- Keep Meals Light and Hydrate: Stick to lighter meals and drink plenty of water after your session. Avoid high-dose antioxidants like vitamin C for the next 24 hours, since they may reduce the oxidative effect that ozone is meant to produce.
- Leave the Bandages On: Keep the bandages over the IV sites for about four to five hours to minimize bruising and protect the area while it closes fully.
- Expect Mild Fatigue or Aches: You may feel a little tired or achy after your treatment, and you may have a headache. This is temporary and usually passes within a few hours. Plan to take it easy for the rest of the day if you can.
- Avoid Intense Workouts: Skip heavy exercise right after your session. Light movement, like walking, is fine, but give your body space to rest and adjust.
- Watch How You Feel: Most patients feel fine afterward, but let us know if anything feels unusual or stronger than expected. We are here to help you through every step of the process.
FAQs About EBOO
How Soon Will I Notice the Results of EBOO Treatments?
Some patients begin to feel subtle changes within the first week, especially if inflammation or fatigue is part of what they are addressing. Others may need multiple sessions before noticing a difference. Each body responds at its own pace, and your results will depend on your health status and the systems involved. We evaluate progress as we go and adjust the protocol as needed.
How Many Treatments Will I Need?
Most patients begin with a series of three sessions spaced about one week apart. Some continue with maintenance sessions every few months, depending on their goals and response. We can reassess after the first round to determine if repeating the series would be useful. Each plan is designed around what makes sense for your health and recovery.
Who Is a Good Candidate for EBOO?
We recommend EBOO treatment for adults who are stable enough for IV therapy and are looking to support systemic health. You should not be actively fighting an uncontrolled infection or have certain bleeding disorders. If you are pregnant or currently receiving chemotherapy, we may explore other options instead. A full evaluation helps us confirm whether EBOO makes sense for your situation.
How Much Does EBOO Cost?
EBOO is not typically covered by insurance, so the cost can vary depending on how many sessions you have. We go over all pricing during your initial visit, including package options when appropriate. You will know the full cost before starting, and we encourage questions if anything is unclear.
Explore Our Wellness Services in Naples, FL
EBOO offers a comprehensive approach to filtering toxins, supporting circulation, and optimizing oxygen delivery through a single treatment. At Orchidia Medical Group, we use evidence-informed therapies to support patients looking for real, measurable improvement in how they feel and function. We serve Naples, FL, and surrounding areas, and you can reach us directly at (236) 333-8809 to learn more. To schedule your consultation or ask a question, contact us using our online form.
